A Case of Ipt

A Case of IPT 1. How and where atomic fare 18 platelets produced in the dust? Platelets atomic number 18 produced in the bone mall from very large bone meaning cells called megakaryocytes. As megakaryocytes develop into giant cells, they bear up under a go of fragmentation that runs in the release of over 1,000 platelets per megakaryocyte. 2. Describe the economic consumption played by platelets in hemostasis. Platelets verify the endothelial surface. Loss of circulating platelets cursorily results in changes in the endothelial cells of the capillaries.These changes instance intravascular material to leak into the capillary bed. Platelets initially arrest bleeding in part blood vessels. Platelets provide phospholipids, which acts as the catalytic surface for initiation of the coagulation process that played by platelets in hemostasis. 3. pin down thrombocytopenia and list the more prevalent causes of this condition. Thrombocytopenia is a blood malady characterized by an ab generally wiped out(p) occur of platelets in the bloodstream.Abnormal reductions in the number of platelets are caused when abnormalities occur in any of the pursual three processes decreased platelet production by the bone marrow change magnitude trapping of platelets by the spleen or a more rapid than normal destruction of platelets. People with this condition soft bruise and can have episodes of senseless bleeding. 4. What are the potential consequences of a low platelet count? Your blood would non clot as well in the event of an injury, and you could bleed to death without medical intervention. . What drugs have been associated with the development of thrombocytopenia? around of the drugs associated with the development of Thrombocytopenia are Sulfonylurea drugs, Benzodiazepines deal Diazepam and Anti-epileptic drugs like Carbamazepine. 6. How is thrombocytopenia do by in individuals diagnosed with the condition? The type of word you get would depend on the har d knocks of the case, but some of the possible treatments are blood or platelet transfusions, steroids, immunoglobulin, and a splenectomy. . How might removal of the spleen (splenectomy) result in an increase in the number of circulating platelets? The spleen is supposed to polish off antibodies from RBCs, so without the production of antibodies, the number of platelets should increase. 8. What is idiopathic Thrombocytopenic Purpura (ITP)? ITP is a bleeding upset where blood doesnt clot as well as it should due to a low number of platelets. Source guinea pig Center for Case Study tenet in Science